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Collision Tumors of the Colon and Peritoneum: Signet-Ring Cell Carcinoma and Granular Cell Tumor

Authors :
Dorela-Codruta Lazureanu
Denisa Anderco
Sorin Dema
Aura Jurescu
Remus Cornea
Octavia Vita
Bogdan Tunescu
Sorina Taban
Source :
Life, Vol 13, Iss 12, p 2263 (2023)
Publication Year :
2023
Publisher :
MDPI AG, 2023.

Abstract

Collision tumors, although rare, characterized by two distinctive (morphological, as well immunohistochemical) and spatially independent tumor components at the same location, are always puzzling for clinicians, pathologists, and patients because they do not fit into the usual approaches, being neither diagnostic nor therapeutic. Reviewing the specialized literature, to date, collision tumors have been reported in multiple locations such as the skin, esophagus, stomach, intestine, liver, kidney, bladder, adrenal gland, or thyroid. We report a case of coexistence at the same site of a malignant tumor of the ascending colon and a benign tumor emerging from the peritoneal lining, initially thought by the surgeon to be right-sided serosal carcinomatosis. But histopathological examination reveals that those multiple serosal nodules were benign granular cell tumors that have collided with highly aggressive transparietal signet-ring colon carcinoma. These results put the patient’s prognosis and therapeutic strategy in a different light than the clinical and intraoperative evaluation.

Details

Language :
English
ISSN :
20751729
Volume :
13
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Life
Publication Type :
Academic Journal
Accession number :
edsdoj.15bded9483934b6c92db587cbfc752dd
Document Type :
article
Full Text :
https://doi.org/10.3390/life13122263