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Effects of β-alanine on intestinal development and immune performance of weaned piglets
- Source :
- Animal Nutrition, Vol 12, Iss , Pp 398-408 (2023)
- Publication Year :
- 2023
- Publisher :
- KeAi Communications Co., Ltd., 2023.
-
Abstract
- Beta-alanine is an important amino acid involved in several metabolic reactions in the body. The study aimed to investigate the effect of β-alanine supplementation on intestinal development and the immune performance of weaned piglets. Thirty-two 21-day-old healthy weaned piglets (half female and half male; Duroc × Landrace × Yorkshire) with an initial body weight of 8.11 ± 0.21 kg were randomly divided into 4 groups with 8 replicates of 1 pig each. The control group was fed a basal diet and the three experimental treatment groups were fed diets supplemented with 300, 600 and 1,200 mg/kg β-alanine, respectively. The trial lasted 28 days and the diets fed were divided into 2 phases: the late lactation period (day 1 to 14) and the nursery period (day 15 to 28), during which the weaned piglets had free access to food and water. The regulatory effects of β-alanine were further investigated in vitro using organoids obtained from the jejunum of piglets. In vivo, the addition of β-alanine to the diet had no significant effect on the growth performance of weaned piglets (P > 0.05), but significantly reduced serum levels of immunoglobulin G (IgG) (P
Details
- Language :
- English
- ISSN :
- 24056545
- Volume :
- 12
- Issue :
- 398-408
- Database :
- Directory of Open Access Journals
- Journal :
- Animal Nutrition
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.14de64a92e4547a783c93b1f5a9549
- Document Type :
- article
- Full Text :
- https://doi.org/10.1016/j.aninu.2022.10.008