Back to Search Start Over

Analysis of the Oxidative Stress Regulon Identifies soxS as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

Authors :
João Anes
Katherine Dever
Athmanya Eshwar
Scott Nguyen
Yu Cao
Sathesh K. Sivasankaran
Sandra Sakalauskaitė
Angelika Lehner
Stéphanie Devineau
Rimantas Daugelavičius
Roger Stephan
Séamus Fanning
Shabarinath Srikumar
Source :
mBio, Vol 12, Iss 3 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

Antimicrobial resistance is a global health challenge. Few new antibiotics have been developed for use over the years, and preserving the efficacy of existing compounds is an important step to protect public health. This paper describes a study that examines the effects of exogenously induced oxidative stress on K. pneumoniae

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
21507511
Volume :
12
Issue :
3
Database :
Directory of Open Access Journals
Journal :
mBio
Publication Type :
Academic Journal
Accession number :
edsdoj.14a94f637a5743119c7891bd75fb49a9
Document Type :
article
Full Text :
https://doi.org/10.1128/mBio.00867-21