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(Anthracen-9-yl)(piperidin-1-yl)methanone

Authors :
Hua-You Hu
Yu-Cheng Huang
Hai-Tao Yu
Yan Zhang
Source :
Acta Crystallographica Section E, Vol 64, Iss 11, Pp o2120-o2120 (2008)
Publication Year :
2008
Publisher :
International Union of Crystallography, 2008.

Abstract

The title compound, C20H19NO, is a substructure of CP-640186, a potent inhibitor of mammalian acetyl-coenzyme A carboxylases. In the crystal structure, the amide group forms a dihedral angle of 87.0 (1)° with the plane of the anthracene unit and the piperidine ring adopts a chair conformation. Molecules are arranged into layers parallel to (100) and adjacent anthracene units within layers form dihedral angles of 13.2 (1)°. C—H...O interactions from the piperidine rings to the C=O group of the amide are observed between layers.

Subjects

Subjects :
Crystallography
QD901-999

Details

Language :
English
ISSN :
16005368
Volume :
64
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Acta Crystallographica Section E
Publication Type :
Academic Journal
Accession number :
edsdoj.145dd51b03974703b04598a9a5ed29d4
Document Type :
article
Full Text :
https://doi.org/10.1107/S1600536808033205