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Clinical possibilities of HER2-positive breast cancer diagnosis using alternative scaffold proteins

Authors :
O. D. Bragina
V. I. Chernov
S. M. Deyev
V. M. Tolmachev
Source :
Бюллетень сибирской медицины, Vol 21, Iss 3, Pp 132-139 (2022)
Publication Year :
2022
Publisher :
Siberian State Medical University (Tomsk), 2022.

Abstract

HER2-positive breast cancer occurs in 15–20% of breast cancer patients and is associated primarily with a poor prognosis of the disease and the need for highly specific targeted therapy. Despite the clinical importance of determining HER2/neu, traditional diagnostic methods have their disadvantages and require the study of new additional research techniques.The information presented in this review makes it possible to consider current trends in the radionuclide diagnosis of HER2-positive breast cancer using the latest class of alternative scaffold proteins and to consider various aspects of their use in clinical practice.

Details

Language :
English, Russian
ISSN :
16820363 and 18193684
Volume :
21
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Бюллетень сибирской медицины
Publication Type :
Academic Journal
Accession number :
edsdoj.141f865557d04efd9bc5529ae83e4e99
Document Type :
article
Full Text :
https://doi.org/10.20538/1682-0363-2022-3-132-139