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EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAMhigh/CD44+ colorectal cancer stem cells
- Source :
- Türk Biyokimya Dergisi, Vol 47, Iss 5, Pp 620-625 (2022)
- Publication Year :
- 2022
- Publisher :
- De Gruyter, 2022.
-
Abstract
- A small subpopulation of colorectal cancer stem cells (CSCs) possess the ability to self-renew and the capacity to initiate the original tumor. EpCAMhigh/CD44+ cells are regarded as CSCs in colorectal cancer. The present study was undertaken to investigate the significance of EpCAM in the in vitro proliferation ability and oxaliplatin chemoresistance of EpCAMhigh/CD44+ colorectal CSCs.
Details
- Language :
- English
- ISSN :
- 1303829X
- Volume :
- 47
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Türk Biyokimya Dergisi
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.13dea793ef3d46ec9f2ac92a4d1bf523
- Document Type :
- article
- Full Text :
- https://doi.org/10.1515/tjb-2021-0301