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Impact of comorbidities in the decision of using invasive management in elderly patients with NSTEACS

Authors :
Vicente Pernias
José María García Acuña
Sergio Raposeiras-Roubín
José A. Barrabés
Alberto Cordero
Manuel Martínez-Sellés
Alfredo Bardají
Pablo Díez-Villanueva
Francisco Marín
Juan M. Ruiz-Nodar
Nuria Vicente-Ibarra
Gonzalo L. Alonso Salinas
Pedro Rigueiro
Emad Abu-Assi
Francesc Formiga
Julio Núñez
Eduardo Núñez
Albert Ariza-Solé
Juan Sanchis
Source :
REC: Interventional Cardiology (English Ed.), Vol 3, Iss 1, Pp 15-20 (2021)
Publication Year :
2021
Publisher :
Permanyer, 2021.

Abstract

ABSTRACT Introduction and objectives: The presence of comorbidities in elderly patients with non-ST-segment elevation acute coronary syndrome worsens its prognosis. The objective of the study was to analyze the impact of the burden of comorbidities in the decision of using invasive management in these patients. Methods: A total of 7211 patients > 70 years old from 11 Spanish registries were included. Individual data were analyzed in a common database. We assessed the presence of 6 comorbidities and their association with coronary angiography during admission. Results: The mean age was 79 ± 6 years and the mean CRACE score was 150 ± 21 points. A total of 1179 patients (16%) were treated conservatively. The presence of each comorbidity was associated with less invasive management (adjusted for predictive clinical variables): cerebrovascular disease (OR, 0.78; 95%CI, 0.64-0.95; P = .01), anemia (OR, 0.64; 95%CI, 0.54-0.76; P < .0001), chronic kidney disease (OR, 0.65; 95%CI, 0.56-0.75; P < .0001), peripheral arterial disease (OR, 0.79; 95%CI, 0.65-0.96; P = .02), chronic lung disease (OR, 0.85; IC95%, 0.71-0.99; P = .05), and diabetes mellitus (OR, 0.85; 95%CI, 0.74-0.98; P < .03). The increase in the number of comorbidities (comorbidity burden) was associated with a reduction in coronary angiographies after...

Subjects

Subjects :
Medicine

Details

Language :
English, Spanish; Castilian
ISSN :
26047322
Volume :
3
Issue :
1
Database :
Directory of Open Access Journals
Journal :
REC: Interventional Cardiology (English Ed.)
Publication Type :
Academic Journal
Accession number :
edsdoj.1375aed827bf43ae94e3d4deaf31757b
Document Type :
article
Full Text :
https://doi.org/10.24875/RECICE.M20000147