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Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger

Authors :
Ahmed M. Arzika
Ramatou Maliki
E. Brook Goodhew
Eric Rogier
Jeffrey W. Priest
Elodie Lebas
Kieran S. O’Brien
Victoria Le
Catherine E. Oldenburg
Thuy Doan
Travis C. Porco
Jeremy D. Keenan
Thomas M. Lietman
Diana L. Martin
Benjamin F. Arnold
MORDOR-Niger Study Group
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

In a randomized placebo-controlled trial in rural Niger, biannual azithromycin distribution to children 1-59 months reduced all-cause mortality. Based on serology, Arzika et al. here report a reduction of Campylobacter infection, supporting one mechanism for the intervention’s impact on mortality.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.11e4ef4da67450ea59b43805cf25e1c
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-28565-5