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Association between the rs2241883 polymorphism of the fatty acid‐binding protein‐1 (FABP1) gene and obesity in a population of MASHAD study cohort
- Source :
- Molecular Genetics & Genomic Medicine, Vol 11, Iss 7, Pp n/a-n/a (2023)
- Publication Year :
- 2023
- Publisher :
- Wiley, 2023.
-
Abstract
- Abstract Background and Aims The fatty acid‐binding proteins (FABPs) gene polymorphisms are related to several metabolic properties. We investigated the association of SNPs rs2241883 of FABP 1 gene with obesity to evaluate the role of FABP1 gene in the pathogenesis of obesity in the population of MASHAD study cohort. Methods In this cross‐sectional study, 2731 individuals (1883 Obese and 848 nonobese) aged 35 to 65 years old, were enrolled from the Mashhad Stroke and Heart Atherosclerotic Disorder (MASHAD) study cohort. DNA Quantitation was determined using the NanoDrop®‐1000 instrument (NanoDrop‐Technologies). The rs2241883 polymorphisms were genotyped by double ARMs PCR (double amplification refractory mutation system) reactions. Data analysis was carried out using SPSS 22 and a p
- Subjects :
- atherosclerosis
ARMs PCR
FABPs
genotype
metabolic syndrome
Genetics
QH426-470
Subjects
Details
- Language :
- English
- ISSN :
- 23249269
- Volume :
- 11
- Issue :
- 7
- Database :
- Directory of Open Access Journals
- Journal :
- Molecular Genetics & Genomic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.118ae63b8db47b29e348b8cc759678d
- Document Type :
- article
- Full Text :
- https://doi.org/10.1002/mgg3.2173