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The relationship of depression with fatigue, quality of life, and gastrointestinal symptoms in patients with restless legs syndrome

Authors :
Özge Çoban
Mustafa Ertuğrul Yaşa
Ali Rıza Sonkaya
Necmiye Ün Yıldırım
Source :
Gülhane Tıp Dergisi, Vol 65, Iss 2, Pp 86-91 (2023)
Publication Year :
2023
Publisher :
Galenos Publishing House, 2023.

Abstract

Aims:This study examined the relationship between depression with fatigue, quality of life (QoL), and gastrointestinal symptoms in patients with restless legs syndrome (RLS).Methods:This prospective study included patients diagnosed with RLS. Depression, fatigue, QoL and gastrointestinal symptoms were evaluated with Hospital Anxiety and Depression Scale, the Fatigue Severity Scale, RLS QoL Questionnaire and Gastrointestinal Symptom Rating Scale, respectively. Multiple regression was performed to determine the relationship between fatigue, QoL, gastrointestinal symptoms, and depression.Results:The final sample included 19 patients [mean age: 42.6±12.7 years, female: 11 (57.9%)]. The level of depression positively correlated with fatigue, QoL, and gastrointestinal symptoms scores. These variables explained 57.1% of the variance in depression scores in patients with RLS (R=0.755, R2=0.571 F=6.645; p=0.005).Conclusions:This study showed that patients with RLS experience worsening QoL, fatigue, and increased gastrointestinal symptoms with increasing depression scores. Managing RLS may require tackling depression and depression-related symptoms with a multifaceted approach.

Details

Language :
English
ISSN :
21468052
Volume :
65
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Gülhane Tıp Dergisi
Publication Type :
Academic Journal
Accession number :
edsdoj.1170f52f35b4e5ea6563747b286c8c7
Document Type :
article
Full Text :
https://doi.org/10.4274/gulhane.galenos.2022.59389