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Análise do perfil de mães e crianças expostas intraútero ao HIV nascidas em uma maternidade de hospital público terciário do sul do Brasil

Authors :
Nathalia Ventura Stefli
Luis Fernando Matoso Mendes
Andrea Maciel de Oliveira Rossoni
Tony Tannous Tahan
Betina Mendez Alcantara Gabardo
Tatiane Emi Hirose
Source :
Residência Pediátrica, Vol 14, Iss 1 (2024)
Publication Year :
2024
Publisher :
Sociedade Brasileira de Pediatria, 2024.

Abstract

OBJECTIVES: evaluate the profile of children exposed intrauterine to HIV born in a tertiary hospital in southern Brazil, describe the prevalence of children classified as high risk and the rate of vertical transmission in this population. METODOLOGY: cross-sectional analytical-observational study. All HIV-exposed children born in 2019 and 2020 at the Clinical Hospital of the Federal University of Paraná were included. Data were collected from the hospitals operating systems, physical records and SISCEL. Study approved by the hospital ethics committee. RESULTS: 142 patients were included. Among the mothers, 26.06% had a detectable viral load in the last trimester, of which 54.05% were above 1000 copies; 37.32% were diagnosed during pregnancy; 40% of women who were diagnosed during pregnancy had a detectable viral load in the 3rd trimester (p=0.01). Of those who had a detectable viral load in the third trimester, 88.89% used ART irregularly or did not use (p < 0.01); 44.37% of newborns were classified as high risk by the current protocol in the period, while with the current new protocol would be 63.38%. The vertical transmission rate was 1.41%. There was 42.26% of loss of follow-up. CONCLUSION: the prevalence of vertical transmission was low, comparable to developed countries. Quality prenatal care, early diagnosis and adherence to ART are factors that modify the rates of vertical transmission of HIV due to the reduction of maternal viral load in the third trimester.

Details

Language :
English, Portuguese
ISSN :
22366814
Volume :
14
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Residência Pediátrica
Publication Type :
Academic Journal
Accession number :
edsdoj.116d71a318144ad196915946c8d59f29
Document Type :
article
Full Text :
https://doi.org/10.25060/residpediatr-2024.v14n1-942