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Vitamin D binding protein in psychiatric and neurological disorders: Implications for diagnosis and treatment

Authors :
Ling Li
Bing Han
Yan Kong
Gaojia Zhang
Zhijun Zhang
Source :
Genes and Diseases, Vol 11, Iss 5, Pp 101309- (2024)
Publication Year :
2024
Publisher :
KeAi Communications Co., Ltd., 2024.

Abstract

Vitamin D binding protein (VDBP) serves as a key transporter protein responsible for binding and delivering vitamin D and its metabolites to target organs. VDBP plays a crucial part in the inflammatory reaction following tissue damage and is engaged in actin degradation. Recent research has shed light on its potential role in various diseases, leading to a growing interest in understanding the implications of VDBP in psychiatric and neurological disorders. The purpose of this review was to provide a summary of the existing understanding regarding the involvement of VDBP in neurological and psychiatric disorders. By examining the intricate interplay between VDBP and these disorders, this review contributes to a deeper understanding of underlying mechanisms and potential therapeutic avenues. Insights gained from the study of VDBP could pave the way for novel strategies in the diagnosis, prognosis, and treatment of psychiatric and neurological disorders.

Details

Language :
English
ISSN :
23523042
Volume :
11
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Genes and Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.1142951500bd4b3091fa10d59b8c4095
Document Type :
article
Full Text :
https://doi.org/10.1016/j.gendis.2024.101309