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Optical coherence tomography angiography quantitative analysis of the effect of modified Buyang Huanwu Decoction on blood flow to the optic disc in patients with non-proliferative diabetic retinopathy
- Source :
- Guoji Yanke Zazhi, Vol 23, Iss 12, Pp 2040-2045 (2023)
- Publication Year :
- 2023
- Publisher :
- Press of International Journal of Ophthalmology (IJO PRESS), 2023.
-
Abstract
- AIM:To observe the clinical efficacy of modified Buyang Huanwu Decoction in treating non-proliferative diabetic retinopathy(NPDR)of qi and yin deficiency and stagnation of collaterals, and to quantitatively analyze the changes in peripapillary vessel density before and after treatment using optical coherence tomography angiography(OCTA).METHODS:A randomized controlled trial was used to collect a total of 58 patients(99 eyes)with qi and yin deficiency and stagnation of collaterals NPDR who visited our hospital from June 2022 to November 2022, and patients were randomly divided into an observation group(n=29, 51 eyes)and a control group(n=29, 48 eyes). The control group received basic treatment according to the recommendations for DR published by the American Academy of Ophthalmology in 2019(blood glucose control, diabetes health education, and regular follow-up for patients with mild NPDR; and add local/grid-like laser photocoagulation if necessary for patients with moderate NPDR), while the observation group received modified Buyang Huanwu Decoction in addition to the basic treatment for 1mo. The best-corrected visual acuity(BCVA), traditional Chinese medicine(TCM)efficacy, peripapillary telangiectasia vessel density(ppVD), and changes in peripapillary retinal nerve fiber layer(pRNFL)thickness were compared between the two groups before and after treatment.RESULTS:The BCVA(LogMAR)of the observation group was 0.20(0.10, 0.30)after 1mo of treatment, which was significantly improved compared with that of the control group of 0.30(0.20, 0.40; P
Details
- Language :
- English
- ISSN :
- 16725123
- Volume :
- 23
- Issue :
- 12
- Database :
- Directory of Open Access Journals
- Journal :
- Guoji Yanke Zazhi
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.1091cc668111450bba30724f5975ffa7
- Document Type :
- article
- Full Text :
- https://doi.org/10.3980/j.issn.1672-5123.2023.12.20