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Effective prophylaxis of visual and neurological disturbances with an anti-endothelin drug: analysis of 1642 sclerotherapy sessions
- Source :
- Veins and Lymphatics, Vol 5, Iss 2 (2016)
- Publication Year :
- 2016
- Publisher :
- PAGEPress Publications, 2016.
-
Abstract
- In the literature cases of stroke and transient neurological symptoms have been described after sclerotherapy for chronic venous disease The initial interpretation of these phenomena was that of a micro air embolism in association with a patent foramen ovale. This explanation did not always manage to justify all neurological manifestations. Recent theories have demonstrated that in the area of sclerosis, a significant amount of endothelin 1. We carried out a retrospective assessment of sclerotherapy case studies on 540 patients at ten phlebological centres to search for a relationship between the use of aminaftone (a venotropic drug with demonstrated anti-endothelin action) and the occurrence of side effects after sclerotherapy was performed. Significant reduction of side effects was observed in sclerotherapy for teleangectasias and in patients with migraine history.
Details
- Language :
- English
- ISSN :
- 22797483
- Volume :
- 5
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Veins and Lymphatics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0fd5a4e15fa24e4d89c65c6774d00165
- Document Type :
- article
- Full Text :
- https://doi.org/10.4081/vl.2016.5764