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Mortality, survival and prognostic factors of people with AIDS in intensive care unit
- Source :
- Revista da Escola de Enfermagem da USP, Vol 55 (2021)
- Publication Year :
- 2021
- Publisher :
- SciELO, 2021.
-
Abstract
- ABSTRACT Objective: To analyze mortality, survival and prognostic factors of patients with AIDS in Intensive Care Unit (ICU). Method: Retrospective cohort study with a sample of 202 patients with AIDS in ICU, whose sociodemographic, epidemiological, and clinical characteristics were obtained from medical records and assessed. Results: Patients were mostly male (73.8%) and drug users (59.4%), with no regular health follow-up (61.4%) and no adherence to antiretrovirals (40.6%), presenting low CD4+ T lymphocyte count (94.0%) and high viral load (44.6%). The main causes of hospitalization were sepsis and respiratory and renal insufficiency. The mean duration of hospitalization was 11.9 days (p = 0.0001), with a 41.6% survival; 58.5% died in the ICU. Sepsis upon admission (p < 0.001), pressure injury (p = 0.038), sexual exposure (p = 0.002), high viral load (p = 0.00001) and prolonged hospitalization (p < 0.001) increased the risk of death. Conclusion: Most patients had no regular health follow-up, were drug users and presented low CD4+ T lymphocyte count and high viral load. The high mortality indicated that antiretroviral adherence is essential to reduce viral resistance, opportunistic diseases, and mortality.
Details
- Language :
- English, Spanish; Castilian, Portuguese
- ISSN :
- 1980220X and 1980220x
- Volume :
- 55
- Database :
- Directory of Open Access Journals
- Journal :
- Revista da Escola de Enfermagem da USP
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0f5a027c447f4062a39b5767e7f6a441
- Document Type :
- article
- Full Text :
- https://doi.org/10.1590/1980-220x-reeusp-2021-0121