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Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants

Authors :
Felix Wojcik
Geoffrey P. Dann
Leslie Y. Beh
Galia T. Debelouchina
Raphael Hofmann
Tom W. Muir
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Ubiquitylation of H2B is associated with transcription and regulation of chromatin structure. Here, the authors perform an unbiased screen to identify the role of chromatin modifications on ubiquitylation of H2BK120 and characterize the crosstalk between H2BK120ub and H2A modifications and variants.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.0f57f5223d79484f8c00e20c85b246c0
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-03895-5