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Whipple Disease Presenting as Isolated Transverse Myelitis with Permanent Neurological Damage in a Patient with Systemic Lupus Erythematosus: A Case Report of a Difficult Diagnosis with a Literature Review

Authors :
Carolina Saffioti
Marta Nebiolo
Roberta Caorsi
Alessio Mesini
Mariasavina Severino
Giacomo Brisca
Elio Castagnola
Marco Gattorno
Source :
Infectious Disease Reports, Vol 16, Iss 2, Pp 269-280 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

We describe an atypical case of Whipple disease exclusively involving the spinal cord in an adolescent receiving immunosuppressive therapy for systemic lupus erythematosus. The diagnosis was particularly difficult since lupus and Whipple disease can present similar clinical features and the patient’s prolonged contact with sewage was initially not mentioned. A literature review of the clinical, imaging, diagnostic, and therapeutic challenges of Whipple disease is also performed.

Details

Language :
English
ISSN :
16020022 and 20367449
Volume :
16
Issue :
2
Database :
Directory of Open Access Journals
Journal :
Infectious Disease Reports
Publication Type :
Academic Journal
Accession number :
edsdoj.0e6f99e4c5e47288a8d6dae7aaa0e63
Document Type :
article
Full Text :
https://doi.org/10.3390/idr16020022