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Effect of remote ischemic postconditioning in inflammatory changes of the lung parenchyma of rats submitted to ischemia and reperfusion

Authors :
Rafael Cantero Dorsa
José Carlos Dorsa Vieira Pontes
Andréia Conceição Brochado Antoniolli
Guilherme Viotto Rodrigues da Silva
Ricardo Adala Benfatti
Carlos Henrique Marques dos Santos
Elenir Rose Cury Pontes
José Anderson Souza Goldiano
Source :
Brazilian Journal of Cardiovascular Surgery, Vol 30, Iss 3, Pp 353-359 (2015)
Publication Year :
2015
Publisher :
Sociedade Brasileira de Cirurgia Cardiovascular, 2015.

Abstract

AbstractObjective:To assess the effects of postconditioning remote in ischemia-reperfusion injury in rat lungs.Methods:Wistar rats (n=24) divided into 3 groups: GA (I/R) n=8, GB (R-Po) n=8, CG (control) n=8, underwent ischemia for 30 minutes artery occlusion abdominal aorta, followed by reperfusion for 60 minutes. Resected lungs and performed histological analysis and classification of morphological findings in accordance with the degree of tissue injury. Statistical analysis of the mean rating of the degree of tissue injury.Results:GA (3.6), GB (1.3) and CG (1.0). (GA GB X P

Details

Language :
English
ISSN :
16789741
Volume :
30
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Brazilian Journal of Cardiovascular Surgery
Publication Type :
Academic Journal
Accession number :
edsdoj.0e2b21fe04df4904b905ae3c9586fd96
Document Type :
article
Full Text :
https://doi.org/10.5935/1678-9741.20150005