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Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation

Authors :
J. Israel Martínez-López
H.A. Betancourt
Erika García-López
Ciro A. Rodriguez
Hector R. Siller
Source :
Micromachines, Vol 8, Iss 5, p 144 (2017)
Publication Year :
2017
Publisher :
MDPI AG, 2017.

Abstract

We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%.

Details

Language :
English
ISSN :
2072666X
Volume :
8
Issue :
5
Database :
Directory of Open Access Journals
Journal :
Micromachines
Publication Type :
Academic Journal
Accession number :
edsdoj.0e1ef1f7e2242fcb87d0fdc0fee5776
Document Type :
article
Full Text :
https://doi.org/10.3390/mi8050144