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Association between COVID-19 Vaccine Side Effects and Body Mass Index in Spain

Authors :
Isabel Iguacel
Aurelio Luna Maldonado
Aurelio Luna Ruiz-Cabello
Marta Casaus
Luis Alberto Moreno
Begoña Martínez-Jarreta
Source :
Vaccines, Vol 9, Iss 11, p 1321 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

COVID-19 vaccines have shown high efficacy, with most side effects being mild–moderate and more frequently reported by females and people at younger ages. Since no studies have assessed the impact that weight status could have on the reported adverse reactions, we aim to study the association between weight status and reported side effects. We included data on 2136 adults from an online survey conducted from 6 May to 9 June 2021. The questionnaire was filled in by participants over Google forms. Generalized Linear Mixed Models were used. A higher risk of presenting fever ≥38°, vomiting, diarrhea and chills was found in those with a non-overweight status compared to those overweight after adjusting for age, sex, education, medication to prevent/relieve post-vaccination effects and vaccine administered. When adjusting, most of the significant effects, in the association between side effects of the COVID-19 vaccine and weight status, did not remain significant. In conclusion, a non-overweight status was associated with a higher risk of presenting fever ≥38°, vomiting, diarrhea and chills compared to those overweight. Nevertheless, most of the reported side effects to COVID-19 vaccine were not associated with a higher risk of presenting more adverse effects, and individual differences were determined by sex and age.

Details

Language :
English
ISSN :
2076393X
Volume :
9
Issue :
11
Database :
Directory of Open Access Journals
Journal :
Vaccines
Publication Type :
Academic Journal
Accession number :
edsdoj.0de24d36791409583c373aa57a3377a
Document Type :
article
Full Text :
https://doi.org/10.3390/vaccines9111321