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B. infantis EVC001 Is Well-Tolerated and Improves Human Milk Oligosaccharide Utilization in Preterm Infants in the Neonatal Intensive Care Unit

Authors :
Sarah Bajorek
Rebbeca M. Duar
Maxwell Corrigan
Christa Matrone
Kathryn A. Winn
Susan Norman
Ryan D. Mitchell
Orla Cagney
Alexander A. Aksenov
Alexey V. Melnik
Evguenia Kopylova
Jose Perez
Source :
Frontiers in Pediatrics, Vol 9 (2022)
Publication Year :
2022
Publisher :
Frontiers Media S.A., 2022.

Abstract

Not all infants carry specialized gut microbes, meaning they cannot digest human milk oligosaccharides and therefore do not receive complete benefits from human milk. B. infantis EVC001 is equipped to convert the full array of complex oligosaccharides into compounds usable by the infant, making it an ideal candidate to stabilize gut function and improve nutrition in preterm infants. A prospective, open-label study design was used to evaluate the tolerability of B. infantis EVC001 and its effects on the fecal microbiota in preterm infants in a Neonatal Intensive Care Unit. Thirty preterm infants

Details

Language :
English
ISSN :
22962360
Volume :
9
Database :
Directory of Open Access Journals
Journal :
Frontiers in Pediatrics
Publication Type :
Academic Journal
Accession number :
edsdoj.0dd1021cfaee4696aa69084aadd66431
Document Type :
article
Full Text :
https://doi.org/10.3389/fped.2021.795970