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Lack of Lloviu Virus Disease Development in Ferret Model

Authors :
Paige Fletcher
Kyle L. O’Donnell
Joseph F. Rhoderick
Corey W. Henderson
Atsushi Okumura
Trenton Bushmaker
Ayato Takada
Chad S. Clancy
Gábor Kemenesi
Andrea Marzi
Source :
Emerging Infectious Diseases, Vol 30, Iss 12, Pp 2639-2642 (2024)
Publication Year :
2024
Publisher :
Centers for Disease Control and Prevention, 2024.

Abstract

The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a disease model for LLOV.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
30
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.0d073039ea46ca99e0cd7f8b51be74
Document Type :
article
Full Text :
https://doi.org/10.3201/eid3012.240818