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A Computerized Cognitive Test Battery for Detection of Dementia and Mild Cognitive Impairment: Instrument Validation Study

Authors :
Siao Ye
Kevin Sun
Duong Huynh
Huy Q Phi
Brian Ko
Bin Huang
Reza Hosseini Ghomi
Source :
JMIR Aging, Vol 5, Iss 2, p e36825 (2022)
Publication Year :
2022
Publisher :
JMIR Publications, 2022.

Abstract

BackgroundEarly detection of dementia is critical for intervention and care planning but remains difficult. Computerized cognitive testing provides an accessible and promising solution to address these current challenges. ObjectiveThe aim of this study was to evaluate a computerized cognitive testing battery (BrainCheck) for its diagnostic accuracy and ability to distinguish the severity of cognitive impairment. MethodsA total of 99 participants diagnosed with dementia, mild cognitive impairment (MCI), or normal cognition (NC) completed the BrainCheck battery. Statistical analyses compared participant performances on BrainCheck based on their diagnostic group. ResultsBrainCheck battery performance showed significant differences between the NC, MCI, and dementia groups, achieving 88% or higher sensitivity and specificity (ie, true positive and true negative rates) for separating dementia from NC, and 77% or higher sensitivity and specificity in separating the MCI group from the NC and dementia groups. Three-group classification found true positive rates of 80% or higher for the NC and dementia groups and true positive rates of 64% or higher for the MCI group. ConclusionsBrainCheck was able to distinguish between diagnoses of dementia, MCI, and NC, providing a potentially reliable tool for early detection of cognitive impairment.

Subjects

Subjects :
Geriatrics
RC952-954.6

Details

Language :
English
ISSN :
25617605
Volume :
5
Issue :
2
Database :
Directory of Open Access Journals
Journal :
JMIR Aging
Publication Type :
Academic Journal
Accession number :
edsdoj.0cff48760c4a1884fbd4a9191c2c29
Document Type :
article
Full Text :
https://doi.org/10.2196/36825