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Cardiac surgical outcomes of patients with heterotaxy syndromeCentral MessagePerspective

Authors :
Manan H. Desai, MD
Nicolle M. Ceneri, MD
Zaenab Dhari, MD
Aybala Tongut, MD
Mahmut Ozturk, MD
Steven J. Staffa, MS
David Zurakowski, MS, PhD
David Schidlow, MD, MMus
Pranava Sinha, MD
Richard A. Jonas, MD
Can Yerebakan, MD
Source :
JTCVS Open, Vol 13, Iss , Pp 292-306 (2023)
Publication Year :
2023
Publisher :
Elsevier, 2023.

Abstract

Objectives: The study objectives were to analyze the outcomes of pediatric patients with heterotaxy syndrome undergoing cardiovascular surgery and to determine the predictors of mortality. Methods: A retrospective analysis of 82 patients diagnosed with heterotaxy syndrome who underwent cardiovascular surgery between January 2008 and December 2017 was performed. Univariate and multivariable Cox regression analyses to determine risk factors for mortality and Kaplan–Meier analysis for survival were performed. Results: Patient mortality in the cohort was 34% (28/82), including 36% (20/55) for single ventricle palliation and 30% (8/27) for biventricular repair. At 5 years, the probability of survival did not differ between the groups by log-rank testing (P = .829). Multivariable analysis found extracorporeal membrane oxygenation support (hazard ratio, 10.4; 95% confidence interval, 4.3-25.4; P

Details

Language :
English
ISSN :
26662736
Volume :
13
Issue :
292-306
Database :
Directory of Open Access Journals
Journal :
JTCVS Open
Publication Type :
Academic Journal
Accession number :
edsdoj.0cc66f755af24ec583e98a24ca6506bd
Document Type :
article
Full Text :
https://doi.org/10.1016/j.xjon.2022.12.004