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Mesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury

Authors :
Feiyan Lin
Wenyi Chen
Jiahang Zhou
Jiaqi Zhu
Qigu Yao
Bing Feng
Xudong Feng
Xiaowei Shi
Qiaoling Pan
Jiong Yu
Lanjuan Li
Hongcui Cao
Source :
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Publication Year :
2022
Publisher :
Nature Publishing Group, 2022.

Abstract

Schematic diagram of the protective effect of MSC-derived exosomes on maintaining SLC7A11 function during ferroptosis involved in CCl4-induced ALI.

Subjects

Subjects :
Cytology
QH573-671

Details

Language :
English
ISSN :
20414889
Volume :
13
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Cell Death and Disease
Publication Type :
Academic Journal
Accession number :
edsdoj.0c764b2efaca41e790c5973e9816cad8
Document Type :
article
Full Text :
https://doi.org/10.1038/s41419-022-04708-w