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Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system

Authors :
Julia Ramírez
Stefan van Duijvenboden
Ioanna Ntalla
Borbala Mifsud
Helen R Warren
Evan Tzanis
Michele Orini
Andrew Tinker
Pier D. Lambiase
Patricia B. Munroe
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Genome-wide association studies have identified multiple loci for resting heart rate (HR) but the genetic factors associated with HR increase during and HR recovery after exercise are less well studied. Here, the authors examine both traits in a two-stage GWAS design in up to 67,257 individuals from UK Biobank.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.0b8087cae154c7b97a4bbad5718ef4b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-04148-1