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Letrozole Induced Hypercalcemia in a Patient with Breast Cancer
- Source :
- Case Reports in Oncological Medicine, Vol 2014 (2014)
- Publication Year :
- 2014
- Publisher :
- Hindawi Limited, 2014.
-
Abstract
- Hypersecretion of PTHrP is a relatively common cause of malignancy-related hypercalcemia. However, there is only one case report of letrozole induced hypercalcemia. A 52-year-old female patient was referred to our clinic because of the recent discovery of hypercalcemia (11.0 mg/dL). The patient had a history of left breast carcinoma. She had started a course of letrozole (aromatase inhibitor; 2.5 mg dose/day) ten months earlier. Patient’s parathyroid hormone-related protein levels were normal and a bone scintigram revealed no evidence of skeletal metastasis. Other potential causes of high calcium levels were ruled out. We recognized that, when letrozole was taken at one dose daily (2.5 mg), she had recurrent hypercalcemia. Our experience suggests that letrozole may precipitate hypercalcemia in a patient with breast cancer.
- Subjects :
- Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Subjects
Details
- Language :
- English
- ISSN :
- 20906706 and 20906714
- Volume :
- 2014
- Database :
- Directory of Open Access Journals
- Journal :
- Case Reports in Oncological Medicine
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0aafa6f2ead641a2b0cf2ca2cbb12e1a
- Document Type :
- article
- Full Text :
- https://doi.org/10.1155/2014/608585