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Paget’s Disease Mimicking Bone Metastasis in a Patient with Neuroendocrine Tumor on 68Ga-DOTANOC PET/CT

Authors :
Naciye Sinem Gezer
Ali Balci
Özhan Özdogan
Dinç Özaksoy
Source :
Journal of the Belgian Society of Radiology, Vol 100, Iss 1 (2016)
Publication Year :
2016
Publisher :
Ubiquity Press, 2016.

Abstract

Somatostatin (SST) is a neuropeptide present in neurons, endocrine cells, and a wide range of neuroendocrine tumors (NETs). 68Ga-DOTATOC, 68Ga-DOTANOC, and 68Ga-DOTATATE are current SST analogues used for PET/CT which bind to SST receptors expressed in NETs. These SST analogues have been used successfully for diagnosis of SST-expressing tumors with a more sensitive detection technique than conventional scintigraphy. However, there is a lack of clinical data on the differentiation between NETs and other malignant tumors or benign pathological conditions. Here, we report a case of Paget’s disease mimicking bone metastasis of NET on PET/CT due to increased 68Ga-DOTANOC uptake and review examples of similar cases in the literature.

Details

Language :
English
ISSN :
25148281
Volume :
100
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Journal of the Belgian Society of Radiology
Publication Type :
Academic Journal
Accession number :
edsdoj.0aa8400dd234d25bf4f4be5907c1085
Document Type :
article
Full Text :
https://doi.org/10.5334/jbr-btr.903