Back to Search
Start Over
Insulin and leptin levels in overweight and normal-weight Iranian adolescents: The CASPIAN-III study
- Source :
- Journal of Research in Medical Sciences, Vol 19, Iss 5, Pp 387-390 (2014)
- Publication Year :
- 2014
- Publisher :
- Wolters Kluwer Medknow Publications, 2014.
-
Abstract
- Background: In this study, we aim to compare insulin and leptin levels in adolescents with or without excess weight and in those with or without abdominal obesity. Materials and Methods : This case-control study was conducted among 486 samples. We randomly selected 243 overweight and an equal number of normal-weight adolescents from among participants of the third survey of a national surveillance program entitled "Childhood and Adolescence Surveillance and PreventIon of Adult Non-communicable diseases study." Serum insulin and leptin were compared between two groups and their correlation was determined with other variables. Results: The mean age and body mass index (BMI) of participants were 14.10 ± 2.82 years and 22.12 ± 6.49 kg/m 2 , respectively. Leptin and insulin levels were higher in overweight than in normal-weight adolescents (P < 0.05). Leptin level was higher in children with abdominal obesity than in their other counterparts (P < 0.001). Leptin level was correlated with age, fasting blood glucose, BMI, and insulin level. Conclusion: Insulin and leptin levels were higher among overweight and obese children, which may reflect insulin and leptin-resistance. Given the complications of excess weight from early life, prevention and controlling childhood obesity should be considered as a health priority.
Details
- Language :
- English
- ISSN :
- 17351995 and 17357136
- Volume :
- 19
- Issue :
- 5
- Database :
- Directory of Open Access Journals
- Journal :
- Journal of Research in Medical Sciences
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0a425d9b404641faac3b449669b5456b
- Document Type :
- article