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Asymmetric one-pot transformation of isoflavones to pterocarpans and its application in phytoalexin synthesis

Authors :
Philipp Ciesielski
Peter Metz
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Concise total syntheses of 6a-hydroxypterocarpans are sought after due to their broad spectrum of bioactivities. Here, the authors report the asymmetric syntheses of several natural isoflavonoids, including (−)-glyceollin I and (−)-glyceollin II, by means of an asymmetric transfer hydrogenation (ATH) reaction.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.094b56a46bb64a858a89636719aa66bc
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-16933-y