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Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia

Authors :
Julien Bryois
Melanie E. Garrett
Lingyun Song
Alexias Safi
Paola Giusti-Rodriguez
Graham D. Johnson
Annie W. Shieh
Alfonso Buil
John F. Fullard
Panos Roussos
Pamela Sklar
Schahram Akbarian
Vahram Haroutunian
Craig A. Stockmeier
Gregory A. Wray
Kevin P. White
Chunyu Liu
Timothy E. Reddy
Allison Ashley-Koch
Patrick F. Sullivan
Gregory E. Crawford
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Chromatin accessibility may be altered in disease states. Here the authors carry out ATAC-seq on a large number of samples of dorsolateral prefrontal cortex from individuals with schizophrenia, and healthy controls.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.08c8eca6a4644c7a80907c7bfa108e99
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-05379-y