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The olfactory epithelium as a port of entry in neonatal neurolisteriosis

Authors :
Dennis Pägelow
Chintan Chhatbar
Andreas Beineke
Xiaokun Liu
Andreas Nerlich
Kira van Vorst
Manfred Rohde
Ulrich Kalinke
Reinhold Förster
Stephan Halle
Peter Valentin-Weigand
Mathias W. Hornef
Marcus Fulde
Source :
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Publication Year :
2018
Publisher :
Nature Portfolio, 2018.

Abstract

Listeria monocytogenes causes meningitis in newborns. Here, Pägelow et al. present a mouse model of neonatal cerebral listeriosis, and show that nasal inoculation, but not intragastric administration, leads to early brain infection in the absence of bacteraemia during the neonatal period.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
9
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.08c113f11854074a92f5cc129f573b3
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-018-06668-2