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DIAGNOSTIC VALUE OF STUDYING THE LEVELS OF PRO- AND ANTI-INFLAMMATORY CYTOKINES OF THE IMMUNE SYSTEM IN PATIENTS WITH BREAST CANCER
- Source :
- Опухоли женской репродуктивной системы, Vol 0, Iss 3-4, Pp 49-52 (2014)
- Publication Year :
- 2014
- Publisher :
- ABV-press, 2014.
-
Abstract
- The diagnostic value of the serum levels of proinflammatory (TNF-α, IL-1β, IL-6, and IFN-γ) and anti-inflammatory (IL-4 and IL-10) cytokines of the immune system was studied in 54 patients with breast cancer (BC). Analysis identified the increased concen- trations of proinflammatory cytokines, such as IL-1β, TNF-α, and IL-6, in the peripheral sera of BC patients.Analysis of anti-inflammatory cytokines in the peripheral sera of patients with BC also revealed a significant increase in the values of IL-4 and IL-10. The findings suggest that there is imbalance between cellular and humoral immunity factors, the study of which will be an important diagnostic criterion for BC.
Details
- Language :
- Russian
- ISSN :
- 19944098 and 19998627
- Issue :
- 3-4
- Database :
- Directory of Open Access Journals
- Journal :
- Опухоли женской репродуктивной системы
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.083bc4a0ba8a4e7b9981f1e40d121299
- Document Type :
- article
- Full Text :
- https://doi.org/10.17650/1994-4098-2009-0-3-4-49-52