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Coloration in Equine: Overview of Candidate Genes Associated with Coat Color Phenotypes

Authors :
Xiaotong Liu
Yongdong Peng
Xinhao Zhang
Xinrui Wang
Wenting Chen
Xiyan Kou
Huili Liang
Wei Ren
Muhammad Zahoor Khan
Changfa Wang
Source :
Animals, Vol 14, Iss 12, p 1802 (2024)
Publication Year :
2024
Publisher :
MDPI AG, 2024.

Abstract

Variation in coat color among equids has attracted significant interest in genetics and breeding research. The range of colors is primarily determined by the type, concentration, and distribution of melanin pigments, with the balance between eumelanin and pheomelanin influenced by numerous genetic factors. Advances in genomic and sequencing technologies have enabled the identification of several candidate genes that influence coat color, thereby clarifying the genetic basis of these diverse phenotypes. In this review, we concisely categorize coat coloration in horses and donkeys, focusing on the biosynthesis and types of melanin involved in pigmentation. Moreover, we highlight the regulatory roles of some key candidate genes, such as MC1R, TYR, MITF, ASIP, and KIT, in coat color variation. Moreover, the review explores how coat color relates to selective breeding and specific equine diseases, offering valuable insights for developing breeding strategies that enhance both the esthetic and health aspects of equine species.

Details

Language :
English
ISSN :
20762615
Volume :
14
Issue :
12
Database :
Directory of Open Access Journals
Journal :
Animals
Publication Type :
Academic Journal
Accession number :
edsdoj.082b0d37d41a41b284e6b536cf658d83
Document Type :
article
Full Text :
https://doi.org/10.3390/ani14121802