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Human papillomavirus integration perspective in small cell cervical carcinoma

Authors :
Xiaoli Wang
Wenlong Jia
Mengyao Wang
Jihong Liu
Xianrong Zhou
Zhiqing Liang
Qinghua Zhang
Sixiang Long
Suolang Quzhen
Xiangchun Li
Qiang Tian
Xiong Li
Haiying Sun
Caili Zhao
Silu Meng
Ruoqi Ning
Ling Xi
Lin Wang
Shasha Zhou
Jianwei Zhang
Li Wu
Yile Chen
Aijun Liu
Yaqi Ma
Xia Zhao
Xiaodong Cheng
Qing Zhang
Xiaobing Han
Huaxiong Pan
Yuan Zhang
Lili Cao
Yiqin Wang
Shaoping Ling
Lihua Cao
Hui Xing
Chang Xu
Long Sui
Shixuan Wang
Jianfeng Zhou
Beihua Kong
Xing Xie
Gang Chen
Shuaicheng Li
Ding Ma
Shuang Li
Source :
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Publication Year :
2022
Publisher :
Nature Portfolio, 2022.

Abstract

Small cell cervical carcinoma (SCCC) is a rare but aggressive malignancy. Here, the authors report human papillomavirus features and genomic landscape in SCCC via high-throughput sequencing methods and identify MYC, SOX, NR4A, ANKRD and CEA family genes as HPV-integrated hotspots.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
13
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.07e1d7c3f674d149bf1af61c503e9d4
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-022-33359-w