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Prognostic implication of right ventricular-pulmonary artery coupling in valvular heart disease

Authors :
Zhenni Wu
Mingxing Xie
Li Zhang
Qing He
Lang Gao
Mengmeng Ji
Yixia Lin
Yuman Li
Source :
Frontiers in Cardiovascular Medicine, Vol 11 (2025)
Publication Year :
2025
Publisher :
Frontiers Media S.A., 2025.

Abstract

Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RV–PA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs. RV-PA uncoupling has been shown to be associated with poor outcomes in VHD. This review summarizes the prognostic significance of RV-PA coupling in patients with VHD.

Details

Language :
English
ISSN :
2297055X
Volume :
11
Database :
Directory of Open Access Journals
Journal :
Frontiers in Cardiovascular Medicine
Publication Type :
Academic Journal
Accession number :
edsdoj.076badc2b9774efea7037133c8f95ab1
Document Type :
article
Full Text :
https://doi.org/10.3389/fcvm.2024.1504063