Back to Search
Start Over
Fluorescence cystoscopy in patients with non-muscle invasive bladder cancer
- Source :
- Biomedical Photonics, Vol 4, Iss 3, Pp 29-35 (2015)
- Publication Year :
- 2015
- Publisher :
- Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association", 2015.
-
Abstract
- The main challenge of treating non-muscle invasive bladder cancer is multifocal tumors. Current methods of diagnosis are failed to detect all superficial flat tumor lesions in bladder mucosa. The use of fluorescence imaging with 5-aminolevulinic acid (5-ALA) allows to improve the sensibility of routine cystoscopy, but low specificity decreases its diagnostic accuracy. The method of fluorescence imaging combined with local fluorescence spectroscopy developed in P.A. Herzen MCRI has been shown to increase the specificity from 71% to 84%. Thus, local fluorescence spectroscopy in visible fluorescence of 5-ALA-induced protoporphyrin allows to perform guided biopsy and decrease the rate of diagnostic mistakes.
Details
- Language :
- Russian
- ISSN :
- 24139432
- Volume :
- 4
- Issue :
- 3
- Database :
- Directory of Open Access Journals
- Journal :
- Biomedical Photonics
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.070ae78cec2f49c2abb24dd07bbb9fce
- Document Type :
- article
- Full Text :
- https://doi.org/10.24931/2413-9432-2015-4-3-29-35