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Diverse human extracellular RNAs are widely detected in human plasma

Authors :
Jane E. Freedman
Mark Gerstein
Eric Mick
Joel Rozowsky
Daniel Levy
Robert Kitchen
Saumya Das
Ravi Shah
Kirsty Danielson
Lea Beaulieu
Fabio C. P. Navarro
Yaoyu Wang
Timur R. Galeev
Alex Holman
Raymond Y. Kwong
Venkatesh Murthy
Selim E. Tanriverdi
Milka Koupenova
Ekaterina Mikhalev
Kahraman Tanriverdi
Source :
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Publication Year :
2016
Publisher :
Nature Portfolio, 2016.

Abstract

Extracellular miRNAs are present in a variety of bodily fluids. Here, Freedman et al. analysed plasma-derived RNA by RNA-seq from 40 people followed by targeted RT-qPCR in an additional 2,763 people, and report over 1,000 extracellular RNAs including microRNAs, piwi-interacting RNA and small nucleolar RNAs.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
7
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.06f017ada382433883a715f858f681f2
Document Type :
article
Full Text :
https://doi.org/10.1038/ncomms11106