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A Mini Review of S-Nitrosoglutathione Loaded Nano/Micro-Formulation Strategies
- Source :
- Nanomaterials, Vol 13, Iss 2, p 224 (2023)
- Publication Year :
- 2023
- Publisher :
- MDPI AG, 2023.
-
Abstract
- As a potential therapeutic agent, the clinical application of S-nitrosoglutathione (GSNO) is limited because of its instability. Therefore, different formulations have been developed to protect GSNO from degradation, delivery and the release of GSNO at a physiological concentration in the active position. Due to the high water-solubility and small molecular-size of GSNO, the biggest challenges in the encapsulation step are low encapsulation efficiency and burst release. This review summarizes the different nano/micro-formulation strategies of a GSNO related delivery system to provide references for subsequent researchers interested in GSNO encapsulation.
- Subjects :
- S-nitrosoglutathione
formulation
encapsulation
strategies
Chemistry
QD1-999
Subjects
Details
- Language :
- English
- ISSN :
- 20794991
- Volume :
- 13
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Nanomaterials
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.06bfcd7748b84c908d786eaa62e25fbb
- Document Type :
- article
- Full Text :
- https://doi.org/10.3390/nano13020224