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Markers of Polyfunctional SARS-CoV-2 Antibodies in Convalescent Plasma

Authors :
Harini Natarajan
Andrew R. Crowley
Savannah E. Butler
Shiwei Xu
Joshua A. Weiner
Evan M. Bloch
Kirsten Littlefield
Wendy Wieland-Alter
Ruth I. Connor
Peter F. Wright
Sarah E. Benner
Tania S. Bonny
Oliver Laeyendecker
David Sullivan
Shmuel Shoham
Thomas C. Quinn
H. Benjamin Larman
Arturo Casadevall
Andrew Pekosz
Andrew D. Redd
Aaron A. R. Tobian
Margaret E. Ackerman
Source :
mBio, Vol 12, Iss 2 (2021)
Publication Year :
2021
Publisher :
American Society for Microbiology, 2021.

Abstract

Convalescent plasma has been deployed globally as a treatment for COVID-19, but efficacy has been mixed. Better understanding of the antibody characteristics that may contribute to its antiviral effects is important for this intervention as well as offer insights into correlates of vaccine-mediated protection.

Subjects

Subjects :
Microbiology
QR1-502

Details

Language :
English
ISSN :
21507511
Volume :
12
Issue :
2
Database :
Directory of Open Access Journals
Journal :
mBio
Publication Type :
Academic Journal
Accession number :
edsdoj.06bc9967a2e644a7be0d758babdbd5ad
Document Type :
article
Full Text :
https://doi.org/10.1128/mBio.00765-21