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Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

Authors :
Ana Paula S. LEMOS
Claudio T. SACCHI
Maria V. PAIVA
Teresa I. YARA
Carmo Elias A. MELLES
Leonard W. MAYER
Source :
Revista do Instituto de Medicina Tropical de São Paulo, Vol 43, Iss 3, Pp 119-124 (2001)
Publication Year :
2001
Publisher :
Universidade de São Paulo (USP), 2001.

Abstract

We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.

Details

Language :
English
ISSN :
16789946
Volume :
43
Issue :
3
Database :
Directory of Open Access Journals
Journal :
Revista do Instituto de Medicina Tropical de São Paulo
Publication Type :
Academic Journal
Accession number :
edsdoj.0684d7693d495ca42883ad967474e8
Document Type :
article