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Microbiological and cytotoxic perspectives of active PCL/ZnO film for food packaging
- Source :
- Materials Research Express, Vol 7, Iss 2, p 025312 (2020)
- Publication Year :
- 2020
- Publisher :
- IOP Publishing, 2020.
-
Abstract
- Nanoparticles of zinc oxide (ZnO) were added to poly( ε -caprolactone) (PCL), and PCL/ZnO casting films were produced, afterwards films were characterized using Fourier Transform Infrared Spectroscopy (FTIR), x-ray Diffraction (XRD), Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM). Additionally, antimicrobial and cytotoxic parameters were determined using microbial adhesion testing according to JIS Z 2801: 2000 (E) and agar diffusion method according to ISO 10993-5 2009 , respectively. From collected data, the chemical identity of individual components was kept and the surface control could be achieved changing the composition. According to FTIR spectra and using the Lambert-Beer law higher interaction ratios were met for higher ZnO content which is linked to antimicrobial action. As revealed by AFM analysis, at 5% of ZnO, nanoparticles were well dispersed in PCL matrix with uniform surface film. Analyses from antibacterial activity and cytotoxicity suggested pathogenic Staphylococcus aureus growth was hindered in ZnO films; specifically for PCL/ZnO 5% optimal antibacterial activity and toxicity absent were reached. Summing up, PCL/ZnO5% nanocomposites films offer great potential for commercial applications as active food packaging.
Details
- Language :
- English
- ISSN :
- 20531591
- Volume :
- 7
- Issue :
- 2
- Database :
- Directory of Open Access Journals
- Journal :
- Materials Research Express
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.0637a97af724d23985a0634fb6e40e4
- Document Type :
- article
- Full Text :
- https://doi.org/10.1088/2053-1591/ab7569