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Long non-coding RNAs discriminate the stages and gene regulatory states of human humoral immune response

Authors :
Xabier Agirre
Cem Meydan
Yanwen Jiang
Leire Garate
Ashley S. Doane
Zhuoning Li
Akanksha Verma
Bruno Paiva
José I. Martín-Subero
Olivier Elemento
Christopher E. Mason
Felipe Prosper
Ari Melnick
Source :
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Publication Year :
2019
Publisher :
Nature Portfolio, 2019.

Abstract

Long non-coding RNAs (lncRNA) constitute a large fraction of human transcriptome, and are reported, individually, for context-specific regulatory functions. Here the authors expand our understanding by providing a systemic, unbiased annotation of lncRNA to establish an atlas of lncRNA landscape during the induction of human humoral immune responses.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
10
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.05fdd715a72c49e894038be6d9a78247
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-019-08679-z