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A Review on Drug Delivery System for Tumor Therapy

Authors :
Guoxiang Liu
Lina Yang
Guang Chen
Fenghua Xu
Fanghao Yang
Huaxin Yu
Lingne Li
Xiaolei Dong
Jingjing Han
Can Cao
Jingyu Qi
Junzhe Su
Xiaohui Xu
Xiaoxia Li
Bing Li
Source :
Frontiers in Pharmacology, Vol 12 (2021)
Publication Year :
2021
Publisher :
Frontiers Media S.A., 2021.

Abstract

In recent years, with the development of nanomaterials, the research of drug delivery systems has become a new field of cancer therapy. Compared with conventional antitumor drugs, drug delivery systems such as drug nanoparticles (NPs) are expected to have more advantages in antineoplastic effects, including easy preparation, high efficiency, low toxicity, especially active tumor-targeting ability. Drug delivery systems are usually composed of delivery carriers, antitumor drugs, and even target molecules. At present, there are few comprehensive reports on a summary of drug delivery systems applied for tumor therapy. This review introduces the preparation, characteristics, and applications of several common delivery carriers and expounds the antitumor mechanism of different antitumor drugs in delivery carriers in detail which provides a more theoretical basis for clinical application of personalized cancer nanomedicine in the future.

Details

Language :
English
ISSN :
16639812
Volume :
12
Database :
Directory of Open Access Journals
Journal :
Frontiers in Pharmacology
Publication Type :
Academic Journal
Accession number :
edsdoj.058af5f5c694b2880a44e1f1d07666c
Document Type :
article
Full Text :
https://doi.org/10.3389/fphar.2021.735446