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Atezolizumab plus Bevacizumab as a Bridge for Liver Transplant in Hepatocellular Carcinoma

Authors :
Gabriela Azevedo Solino
Raphael Paiva Cock Paiva Cock Ferreira
Luiz Augusto Carneiro D’Albuquerque
Alberto Queiroz Farias
Lívia Zardo Trindade
Vitor Fiorin de Vasconcelos
Mariana Poltronieri Pacheco
Source :
Brazilian Journal of Transplantation, Vol 26 (2023)
Publication Year :
2023
Publisher :
Associação Brasileira de Transplante de Órgãos, 2023.

Abstract

We report the case of a 68-year-old male with alcohol-related cirrhosis, diagnosed with hepatocellular carcinoma (HCC) noteligible for liver transplant. After immunotherapy with atezolizumab associated with bevacizumab, he underwent a successful living donor liver transplantation (LT), not showing disease evidence or graft injury, maintaining clinically and radiologically stable 14 months after surgery. This is a successful report of combined atezolizumab plus bevacizumab being used as a bridge to LT in a patient with HCC, showing an important finding in therapy in patients with unresectable tumors at diagnosis.

Details

Language :
English, Spanish; Castilian, Portuguese
ISSN :
27641589
Volume :
26
Database :
Directory of Open Access Journals
Journal :
Brazilian Journal of Transplantation
Publication Type :
Academic Journal
Accession number :
edsdoj.056cbc38f26e4a5487a296276501867b
Document Type :
article