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Adaptation of the master antioxidant response connects metabolism, lifespan and feather development pathways in birds

Authors :
Gianni M. Castiglione
Zhenhua Xu
Lingli Zhou
Elia J. Duh
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Fast metabolisms tend to shorten lifespans by increasing oxidative damage. This study identifies a gene mutation that keeps a key antioxidant response active, possibly allowing Neoaves bird species to avoid the tradeoff between rapid metabolism and longevity that challenges most mammals, including humans.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.052bff029c4a47f4a9278f810bbc446b
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-16129-4