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Genetically encoded mediators for sonogenetics and their applications in neuromodulation
- Source :
- Frontiers in Cellular Neuroscience, Vol 17 (2023)
- Publication Year :
- 2023
- Publisher :
- Frontiers Media S.A., 2023.
-
Abstract
- Sonogenetics is an emerging approach that harnesses ultrasound for the manipulation of genetically modified cells. The great penetrability of ultrasound waves enables the non-invasive application of external stimuli to deep tissues, particularly advantageous for brain stimulation. Genetically encoded ultrasound mediators, a set of proteins that respond to ultrasound-induced bio-effects, play a critical role in determining the effectiveness and applications of sonogenetics. In this context, we will provide an overview of these ultrasound-responsive mediators, delve into the molecular mechanisms governing their response to ultrasound stimulation, and summarize their applications in neuromodulation.
Details
- Language :
- English
- ISSN :
- 16625102 and 32016514
- Volume :
- 17
- Database :
- Directory of Open Access Journals
- Journal :
- Frontiers in Cellular Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.04cbb320165147ef9e5a4103438f01b1
- Document Type :
- article
- Full Text :
- https://doi.org/10.3389/fncel.2023.1326279