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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
- Source :
- PLoS ONE, Vol 12, Iss 9, p e0185083 (2017)
- Publication Year :
- 2017
- Publisher :
- Public Library of Science (PLoS), 2017.
-
Abstract
- Variability in red blood cell volumes (distribution width, RDW) increases with age and is strongly predictive of mortality, incident coronary heart disease and cancer. We investigated inherited genetic variation associated with RDW in 116,666 UK Biobank human volunteers.A large proportion RDW is explained by genetic variants (29%), especially in the older group (60+ year olds, 33.8%,
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 12
- Issue :
- 9
- Database :
- Directory of Open Access Journals
- Journal :
- PLoS ONE
- Publication Type :
- Academic Journal
- Accession number :
- edsdoj.04a4afe477254fa0ac97b5879cde81ff
- Document Type :
- article
- Full Text :
- https://doi.org/10.1371/journal.pone.0185083