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The Importance of Diet in Predicting the Remission of Urticaria—Determination of Allergen-Specific IgE

Authors :
Monica Iuliana Ungureanu
Liliana Sachelarie
Radu Ciorap
Bogdan Aurelian Stana
Irina Croitoru
Tudor Ovidiu Popa
Source :
Medicina, Vol 57, Iss 7, p 679 (2021)
Publication Year :
2021
Publisher :
MDPI AG, 2021.

Abstract

Background and Objectives: Different types of food introduced gradually in the diet will expose children to different food allergens, increasing the chance of developing allergic diseases. The aim of our study was to determine if allergen-specific IgE values can influence, depending on the diet, the prediction of remission of urticaria in children. Materials and Methods: This prospective study was conducted in 132 patients diagnosed over two years with urticaria, admitted to “Sf. Maria” Clinical Pediatric Hospital Iaşi. Total IgE assay was performed by ELISA, and determination of specific serum IgE by the CLA System Quanti Scan method (Innogenetics, Heiden, Germany). Data were gathered and statistical analysis was performed using statistical software SPSS, using descriptive and inferential statistics. Results: The determination of specific IgE to food allergens was performed on a total of 132 cases. The values of specific IgE were positive for one or more food allergens in 84 patients (63.64%). The most common allergens involved were: cow’s milk in 33.3% cases, egg white in 22.6% cases, and hazelnuts in 11.9% cases. The specific IgE values for the different types of food included in our study had a predictive value for disease remission. Conclusions: The determination of specific IgE confirms the presence of a particular food allergen and may have predictive value for the future development of an allergic manifestation.

Details

Language :
English
ISSN :
57070679, 16489144, and 1010660X
Volume :
57
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Medicina
Publication Type :
Academic Journal
Accession number :
edsdoj.04211acaacb14f32aee361753de7ccba
Document Type :
article
Full Text :
https://doi.org/10.3390/medicina57070679