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Dutch population structure across space, time and GWAS design

Authors :
Ross P. Byrne
Wouter van Rheenen
Project MinE ALS GWAS Consortium
Leonard H. van den Berg
Jan H. Veldink
Russell L. McLaughlin
Source :
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Publication Year :
2020
Publisher :
Nature Portfolio, 2020.

Abstract

Genetic variation in modern humans can reveal information about a population’s history and migration patterns. Here, the authors describe the ancestry and geospatial genetic structure of the Netherlands, and demonstrate the utility of haplotype-based covariates in genome-wide association studies.

Subjects

Subjects :
Science

Details

Language :
English
ISSN :
20411723
Volume :
11
Issue :
1
Database :
Directory of Open Access Journals
Journal :
Nature Communications
Publication Type :
Academic Journal
Accession number :
edsdoj.03f3a68c977f4d85996f5fe59dbf86ba
Document Type :
article
Full Text :
https://doi.org/10.1038/s41467-020-18418-4